A SECRET WEAPON FOR PKRRATING

3B). R526 from your loop among αJ and αI anchors the C-terminal percentage of get more info the activation loop by forming a salt bridge with E458 at The bottom of αEF. Q459 stabilizes the HRD motif by a hydrogen bond to the leading chain carbonyl of R413. The idea from the activation section is stabilized by a hydrogen bond concerning Y454 and